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The Science of Looking Younger, Longer | Episode 6
Lifespan with Dr. David Sinclair
Go to Podcast Page
The Science of Looking Younger, Longer | Episode 6
Lifespan with Dr. David Sinclair
Go to Podcast Page
Matthew LaPlante, David Sinclair
·
39 Clips
·
Feb 9, 2022
The Science of Looking Younger, Longer | Episode 6
Lifespan with Dr. David Sinclair
0 Clips
·
Feb 9, 2022
Top Moments
The rate of nail growth decreases about half a percent per year. And if you measure that, it's a really good indicator of how old you are
biologically.
Nail Growth Rate Decreases 0.5% Per Year, Indicating Biological Age
The rate of your nail growth is a really good indicator of how you're aging or not
aging.
Nail Growth Rate Decreases 0.5% Per Year, Indicating Biological Age
A little bit of sunlight isn't going to hurt you. In fact, you need it ... But you can overwhelm the system. So, if you actually get sunburned, you get red, there's inflammation, swelling of the skin, tenderness, then you know you've overdone
it.
Excess Sunlight Damages DNA, Creating Thymine Dimers
What's in the literature on antioxidants is kind of depressing for longevity. Over the last 30 years, a lot of different antioxidants have been tried—ingesting them, injecting them, genetically modifying mice, putting it on skin—very few results, if
any.
A Growing Number of Cosmetic Creams Contain Resveratrol
I'm actually working on a way to boost NAD in the skin. That product's not ready for prime time yet, but already people have figured out that if you boost NAD levels, it's good for the
skin.
David Sinclair Is Working on a Product That Boosts Skin NAD Levels
We foresee a day, in my lab, where you can take a pill, maybe three pills, and you'll not just get younger, but your hair will regrow and become dark again if you want it
to.
Tactics That Reverse Skin & Hair Aging Can Be Applied Across the Body
We've evolved, as a species, to have children up until the age of about 30, and then we should stop. Why? Because having kids as a woman is very
dangerous.
Menopausal Hormone Therapy Can Help Women Transition Through Menopause
The health of your skin is super important for the health of the rest of your body and vice
versa.
Skin Is the Body's Largest Organ; It's ~1/6th Your Total Body Weight
If you can keep yourself looking good by doing the right things, you'll probably end up living longer,
too.
David Sinclair Is Excited for the Future of Skin & Hair Anti-Aging
13% of the US has a foot ulcer right
now.
13% of Americans Have a Foot Ulcer; Most Die <5 Years After Diagnosis
Intros & Ads
David Sinclair & Matthew LaPlante Intro
Clips
1
Menopausal Hormone Therapy Can Help Women Transition Through Menopause
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2
AD: Athletic Greens
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3
AD: Levels
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4
AD: InsideTracker
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5
Skin Is the Body's Largest Organ; It's ~1/6th Your Total Body Weight
0
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6
The Skin Pinch Test: The Older You Are, the Longer Your Skin Takes to 'Pop' Back
1
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7
Epidermal Thinning Is a Common Aging Side Effect
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8
13% of Americans Have a Foot Ulcer; Most Die <5 Years After Diagnosis
0
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9
You're as Old as You Look: Older-Looking People Have a Greater Death Risk
1
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10
Exposed to the Elements, Skin Ages Faster Than the Rest of the Body
1
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11
Australia Has High Skin Cancer Rates; Beaches Give Away Free Sunscreen
0
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12
Skin Is Full of Senescent Cells; Senolytic Drugs Reverse Skin Aging
0
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13
Excess Sunlight Damages DNA, Creating Thymine Dimers
0
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14
A Proprietary Peptide in OneSkin Reduces Skin Aging
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15
David Sinclair Debates: Do Collagen Supplements Improve Skin Health?
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16
Retinoids Improve Skin Health By Boosting Collagen & Keratin Production
0
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17
Nail Growth Rate Decreases 0.5% Per Year, Indicating Biological Age
1
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18
Retinoids Reduce Wrinkles But Slow Chaperone-Mediated Autophagy
0
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19
A Growing Number of Cosmetic Creams Contain Resveratrol
0
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20
David Sinclair Is Working on a Product That Boosts Skin NAD Levels
0
Share
21
Found in Many Creams, Hyaluronic Acid May Protect Against Skin Cancer
0
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22
Injectable Hyaluronic Acid Improves Skin Volume Loss & Laxity Best
0
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23
Botox Reduces Wrinkles By Inhibiting Neurotransmission
0
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24
Microneedling Likely Has Hormetic Effects for the Skin
0
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25
The 'No Duh' Skin Health Routine: Avoid Smoking, Excess Sun Exposure, & Alcohol
1
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26
Hair Loss Has a Strong Genetic Component; Is the Mother's Side to Blame?
0
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27
Hundreds of Years Ago, Gray Hair Was a Status Signal
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28
At the Cellular Level, Why Does Hair Loss Occur?
0
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29
Topical Hair Loss Treatments, Like Rogaine, Work By Stimulating Nitric Oxide Production
0
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30
Retinol Cream Slows Hair Thinning, Especially When Combined With Minoxidil
0
Share
31
Propecia for Hair Loss & Why Cutting Off Your Balls Might Increase Longevity
1
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32
Low-Level Laser Therapy Slows Hair Loss Through Mitohormesis
0
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33
Platelet-Rich Plasma Injections Facilitate Hair Regrowth
0
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34
Why Does Hair Start Growing in the Nose & Ears as Men Age?
0
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35
Stress Causes Hair to Turn Gray Via Melanocyte Dysfunction, But It's Reversible
0
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36
Tactics That Reverse Skin & Hair Aging Can Be Applied Across the Body
0
Share
37
David Sinclair Is Excited for the Future of Skin & Hair Anti-Aging
0
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38
David Sinclair Outro
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Transcripts
View Full Episode Transcript
Clips
David Sinclair & Matthew LaPlante Intro
Menopausal Hormone Therapy Can Help Women Transition Through Menopause
AD: Athletic Greens
AD: Levels
AD: InsideTracker
Skin Is the Body's Largest Organ; It's ~1/6th Your Total Body Weight
The Skin Pinch Test: The Older You Are, the Longer Your Skin Takes to 'Pop' Back
Epidermal Thinning Is a Common Aging Side Effect
13% of Americans Have a Foot Ulcer; Most Die <5 Years After Diagnosis
You're as Old as You Look: Older-Looking People Have a Greater Death Risk
Exposed to the Elements, Skin Ages Faster Than the Rest of the Body
Australia Has High Skin Cancer Rates; Beaches Give Away Free Sunscreen
Skin Is Full of Senescent Cells; Senolytic Drugs Reverse Skin Aging
Excess Sunlight Damages DNA, Creating Thymine Dimers
A Proprietary Peptide in OneSkin Reduces Skin Aging
David Sinclair Debates: Do Collagen Supplements Improve Skin Health?
Retinoids Improve Skin Health By Boosting Collagen & Keratin Production
Nail Growth Rate Decreases 0.5% Per Year, Indicating Biological Age
Retinoids Reduce Wrinkles But Slow Chaperone-Mediated Autophagy
A Growing Number of Cosmetic Creams Contain Resveratrol
David Sinclair Is Working on a Product That Boosts Skin NAD Levels
Found in Many Creams, Hyaluronic Acid May Protect Against Skin Cancer
Injectable Hyaluronic Acid Improves Skin Volume Loss & Laxity Best
Botox Reduces Wrinkles By Inhibiting Neurotransmission
Microneedling Likely Has Hormetic Effects for the Skin
The 'No Duh' Skin Health Routine: Avoid Smoking, Excess Sun Exposure, & Alcohol
Hair Loss Has a Strong Genetic Component; Is the Mother's Side to Blame?
Hundreds of Years Ago, Gray Hair Was a Status Signal
At the Cellular Level, Why Does Hair Loss Occur?
Topical Hair Loss Treatments, Like Rogaine, Work By Stimulating Nitric Oxide Production
Retinol Cream Slows Hair Thinning, Especially When Combined With Minoxidil
Propecia for Hair Loss & Why Cutting Off Your Balls Might Increase Longevity
Low-Level Laser Therapy Slows Hair Loss Through Mitohormesis
Platelet-Rich Plasma Injections Facilitate Hair Regrowth
Why Does Hair Start Growing in the Nose & Ears as Men Age?
Stress Causes Hair to Turn Gray Via Melanocyte Dysfunction, But It's Reversible
Tactics That Reverse Skin & Hair Aging Can Be Applied Across the Body
David Sinclair Is Excited for the Future of Skin & Hair Anti-Aging
David Sinclair Outro
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